Blog

• Dextrose injections for failed back surgery syndrome: a consecutive case series

  Posted on: 27-May-2019

  Abstract

  Background Patients with chronic low back pain, who do not respond to conservative treatment methods, generally undergo surgical revision operations, and sometimes an undesirable condition called failed back surgery syndrome (FBSS) may be inevitable. Hereby, dextrose is one of the regenerative methods that has gained popularity in the treatment of many musculoskeletal problems, and we aimed to present and evaluate the outcomes of 5% dextrose for the treatment of FBSS.

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• Treatment of unresolved lower back pain with platelet-rich plasma injections

  Posted on: 18-Feb-2019

  Abstract

  Background Platelet-Rich Plasma (PRP) is a non-invasive modality that has been used to treat musculoskeletal conditions for the past two decades. Based on our research, there were no publications that studied the effect of PRP on unresloved lower back pain. The aim of this study was to report the clinical outcomes of patients who received PRP injections to treat unresolved lower back pain.

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• Single intra-articular platelet-rich plasma versus corticosteroid injections in the treatment of adhesive capsulitis of the shoulder: a cohort study.

  Posted on: 29-Jan-2019

  Abstract

  Objectives To compare the effects of single intra-articular platelet-rich plasma (PRP) and corticosteroid (CS) injections in patients with adhesive capsulitis (AC) of the shoulder. DESIGN:Patients aged 18-70 years of either sex, diagnosed with AC of shoulder, with < 6 months duration were included.

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• Injecting autologous platelet rich plasma solely into the knee joint is not adequate in treating geriatric patients with moderate to severe knee osteoarthritis

  Posted on: 23-Jan-2019

  Abstract

  Knee pain caused by osteoarthritis (OA) is commonly seen in geriatric patients. Patients with knee OA are often complicated with joint pain, soreness, and weakness. The injection of autologous platelet rich plasma (aPRP) has been proven to be effective in treating mild knee OA. The effect of injecting aPRP in treating moderate to severe degrees of knee OA remains controversial.

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• Comparative Study of Local Injection of Platelet Rich Plasma versus Corticosteroids in the Treatment of Lateral Epicondylitis

  Posted on: 04-Jan-2019

  Abstract

  Background Lateral epicondylitis, also known as 'tennis elbow', is a very common condition affecting mainly middle-aged patients that is associated with local tendon pathology, alteration in pain perception and motor impairment. Several approaches to treatment have been proposed, the most frequently used is PRP. Platelet-rich plasma (PRP) is a growing modality for tissue healing, regeneration and has more pain relief lasting effect.

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• Mechanistic insight into hyaluronic acid and platelet-rich plasma-mediated anti-inflammatory and anti-apoptotic activities in osteoarthritic mice

  Posted on: 02-Jan-2019

  Abstract

  Osteoarthritis (OA) poses a major clinical challenges owing to limited regenerative ability of diseased or traumatized chondrocytes in articular cartilage. Previous studies have determined the individual therapeutic efficacies of hyaluronic acid (HA) and platelet-rich plasma (PRP) on OA; however, the underlying mechanism is still lacking. Therefore, we investigated mechanistic approach of HA+PRP therapy on chondrocyte apoptosis in IL-1β+TNF-α (I+T) treated in vitro OA model, in addition to in vivo anterior cruciate ligament transection-OA mice model.

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• High-field MRI exploration of the structural effects of cellular matrix™ on articular cartilage in knee osteoarthritis

  Posted on: 30-Dec-2018

  Objective

  To analyze the potential modulatory effect of Cellular Matrix, a new medical device de-signed for the one-step preparation of platelet-rich plasma in presence of hyaluronic acid, on the structure of articular cartilage in patients suffering from knee osteoarthritis using high-field Magnetic Resonance Imaging measurements of longitudinal relaxation time after gadolinium injection.

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• Comparative evaluation of leukocyte- and platelet-rich plasma and pure platelet-rich plasma for cartilage regeneration in a cartilage defects model in rabbits

  Posted on: 07-Dec-2018

  Abstract

  The increased level of leukocytes in leukocyte- and platelet-rich plasma (L-PRP) may activate NF-κB pathway via interleukin 1β (IL-1β) and tumor necrosis factor α (TNF-α) delivery to counter the beneficial effects of growth factors on cartilage regeneration. The objective of this study is to substantiated that in vivo.

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• The Ozone Revolution

  Posted on: 04-Dec-2018

  What is ozone?

  When oxygen gas (0₂) is exposed to UV radiation or electricity, such as from lightning, the jolt of energy causes it to form ozone (0₃)-the gas that gives the air its characteristic fresh smell after a lightning storm. Carrying an extra oxygen atom, ozone gas is much more reactive than the regular oxygen we breathe in air. It breaks down rapidly, which is why you can't buy it bottled or have it shipped to you.

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• A novel treatment of knee degenerative disorders all-in-one intra-articular injection of platelet-rich plasma combined with hyaluronic acid

  Posted on: 04-Dec-2018

  Purpose

  Therapeutic evaluation of all-in-one intra-articular (IA) injections of autologous platelet rich plasma (PRP) combined with hyaluronic acid (HA) for knee degenerative disorders.

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• Knee OA management: A costeffectiveness analysis of platelet-richplasma versus hyaluronic acid for the intra-articular treatment of knee OA in France

  Posted on: 03-Dec-2018

  Objectives

  The aim of this work is to carry out an economic evaluation of the intra-articular (i.a.) use of the platelet-rich plasma (PRP) therapy in the short period treatment for knee osteoarthritis (OA). Recently the scientific literature has shown the effectiveness of this treatment. The comparator adopted is the Hyaluronic acid (HA) which represents the standard i.a. therapy.

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• Ultrasound guided injection in patellar tendinopathy; clinical outcomes of platelet-rich plasma compared to high-volume injection

  Posted on: 18-Nov-2018

  Abstract

  Objectives To assess the efficacy of ultrasound guided injection of platelet rich plasma versus high volume injection in treatment of patellar tendinopathy, in patients not responding to conservative treatment.

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• Clinical Update: Why PRP Should Be Your First Choice for Injection Therapy in Treating Osteoarthritis of the Knee

  Posted on: 29-Oct-2018

  Abstract

  Purpose of Review: The purpose of this review is to update the reader on the current applications of platelet-rich plasma (PRP) in the treatment of knee osteoarthritis (KOA). This review will focus on PRP’s effect on the osteoarthritic joint, how PRP compares to traditional treatments of KOA, and provide clinical feedback on the use of PRP in an orthopedic and sports medicine practice.

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• Top 5 Headache Causes & Solutions

  Posted on: 22-Oct-2018

  Whether it’s a pounding, throbbing pain or pressure that you feel all over, a headache can stop you in your tracks. You might reach for a Tylenol or Advil, which are great at decreasing the pain, and go about your day. But if the headache is severe enough it can cause sensitivity to light (photophobia), difficulty concentrating and thinking and nausea and vomiting. And you can end up back in bed trying to sleep it off.

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• Efficacy of platelet-rich plasma administration in patients with severe knee osteoarthritis

  Posted on: 08-Oct-2018

  Abstract

  Background/Objective: The efficacy of PRP in knee osteoarthritis (OA) is still a matter of debate. There is evidence to support its use in early knee osteoarthritis but its effectiveness has not yet been established, especially in advanced knee osteoarthritis.

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• A comparison of the use of PRP Versus Hypertonic glucose in the treatment of physiotherapy resistant sacroiliac joint Incompetence

  Posted on: 08-Oct-2018

  Introduction

  The sacroiliac joint (SIJ) can become dysfunctional through trauma and/or pregnancy. The mechanism involves direct or repetitive microtrauma to the buttocks/lower back. Treatment with specialised physiotherapy alleviates the problems in ∼80% of cases. The remainder may respond to prolotherapy (hypertonic glucose injections into the dorsal intra-osseous ligament (DIOL)) after multiple injections. We hypothesised that the response may be more rapid with injection of platelet enriched plasma (PRP) into the DIOL under ultrasound guidance.

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• Treatment of lateral epicondylitis with autologous platelet rich plasma injection

  Posted on: 30-Sep-2018

  Abstract

  Outcomes of traditional treatment methods of lateral epicondylitis are variable because of poor tendon healing properties secondary to poor vascularization. Platelet rich plasma provides locally high concentration of growth factors and have shown its efficacy in many tendinopathies and wound healing. We tried to measure the efficacy of locally injected autologous PRP, subjectively by functional oxford elbow score and pain score as well as objectively by ultrasonographic evaluation of the morphologic changes (focal hypoechoic, odema, tendon thickness, fraying, tear, cortical erosion, calcification) in common extensor origin in 30 patients with mean age of 39.3 years of recalcitrant lateral epicondylitis.

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• Clinical and radiographic comparison of a single LP-PRP injection, a single hyaluronic acid injection and daily NSAID administration with a 52-week follow-up: a randomized controlled trial

  Posted on: 27-Aug-2018

  Abstract

  Background Knee osteoarthritis (OA) is a disease with a high prevalence in the adult population. Nonsteroidal anti-inflammatory drugs (NSAID) or intra-articular injections [hyaluronic acid (HA) or platelet-rich plasma (PRP)] can provide clinical benefit. Magnetic resonance imaging (MRI) has proven to be useful for the evaluation of cartilage volume and thickness in knee osteoarthritis. The purpose of this study was to evaluate the benefit provided by PRP injection in comparison with hyaluronic acid and NSAID in knee OA patients and to compare the radiographic evolution at the 52-week follow-up.

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• The use of Platelet Rich Plasma in the Management of Plantar Fasciitis: A Systematic Review

  Posted on: 13-Aug-2018

  Introduction

  Plantar fasciitis (PF) is the most common cause of heel pain. Approximately 10% of the population develops the condition throughout life. The main symptoms are morning pain and pain at the beginning of activities (after resting time). Pain is felt near the medial and proximal insertion of the plantar fascia in the calcaneus tuberosity, or, less commonly, under heel pad, which leads to dysfunction and limitation for recreational and work activities (Zhiyun et al., 2013; Riddle et al., 2003).

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• Comparative Effect Of Dextrose Prolotherapy And Platelet Rich Plasma Therapy In Primary Osteoarthritis Knee

  Posted on: 08-Aug-2018

  Introduction

  Primary Osteoarthritis knee most common degenerative condition in old age group. Osteoarthritis knee produce greater impact on physical activity and quality of life. Objective & Aim: Evaluate and Compare the effect of Dextrose prolotherapy and Platelet rich plasma therapy on Functional & Clinical outcome.

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