Our office gets calls daily from patients confused about all the health care providers offering regenerative medicine and stem cells. Number one question to ask. Is your health care provider a Certified Physician in regenerative medicine? Most patients do not know that this certification exists.. just like any specialty in medicine, there is a certification.. to be certified is not easy and takes a lot of time, training and testing.
Stem Cell Therapy
Effects of Stromal Cell-Derived Factor-1α Secreted in DegenerativeIntervertebral Disc on Activation and Recruitment of NucleusPulposus-Derived Stem Cells
Stromal cell-derived factor-1α (SDF-1α) plays a significant role in mobilizing and recruiting mesenchymal stem cells (MSCs) to thesites of injury. This study investigated the potential of SDF-1α released in the degenerative intervertebral disc (IVD) to activate andrecruit endogenous nucleus pulposus-derived stem cells (NPSCs) for regenerationin situ.
Bone marrow mesenchymal stem cells in rheumatoid arthritis, spondyloarthritis, and ankylosing spondylitis: problems rather than solutions?
Bone marrow mesenchymal stem cells (BM-MSCs) can dampen inflammation in animal models of inflammatory rheumatisms and human osteoarthritis. They are expected to be a solution for numerous human conditions. However, in rheumatoid arthritis (RA) and spondyloarthritis (SpA), subsets of subchondral BM-MSCs might conversely fuel synovitis and enthesitis.
There are many health care providers( physicians, chiropractors, RNs) around the country talking about stem cell injections. They often give seminars about placenta and amniotic “ stem cell” treatments. Research has shown that most if not all of these products are dead stem cells.
Stem cells, are the latest trend in many areas of medicine. In regenerative Orthopaedics we use the power of these stem cells to help promote healing. Our body has many types of stem cells.
Mesenchymal stem cells (MSCs) possess a broad spectrum of therapeutic applications and have been used in clinical trials. MSCs are mainly retrieved from adult or fetal tissues. However, there are many obstacles with the use of tissue-derived MSCs, such as shortages of tissue sources, difficult and invasive retrieval methods, cell population heterogeneity, low purity, cell senescence, and loss of pluripotency and proliferative capacities over continuous passages.
Bone-related maladies are a major health burden on modern society. Loss of skeletal integrity and regeneration capacity through aging, obesity, and disease follows from a detrimental shift in bone formation and resorption dynamics. Targeting tissue-resident adult stem cells offers a potentially innovative paradigm in the development of therapeutic strategies against organ dysfunction.
The use of stem cells as carriers for therapeutic agents is an appealing modality for targeting tissues or organs of interest. Combined delivery of cells together with various information molecules as therapeutic agents has the potential to enhance, modulate or even initiate local or systemic repair processes, increasing stem cell efficiency for regenerative medicine applications.
Adult stem cells across diverse organs self-renew and differentiate to maintain tissue homeostasis. How stem cells receive input to preserve tissue structure and function largely relies on their communication with surrounding cellular and non-cellular elements.
Native-Osteoarthritic Joint Resident Stem and Progenitor Cells for Cartilage Cell-Based Therapies: A Quantitative Comparison With Respect to Concentration and Biological Performance
Background: Cell-based therapy for cartilage repair is a promising approach and is becoming an established technique. Yet, there is no consensus on the optimal cell source.
What if you could put your own body to work healing itself? That’s the basic premise of regenerative medicine, which is being used in various ways to restore damaged tissues and speed the body’s healing process.
Regenerative medicine - which uses cells to create living, functioning tissue - holds the promise of repairing damaged tissues and organs by stimulating these tissues to heal themselves, according to the National Institutes of Health.