Primary Osteoarthritis knee most common degenerative condition in old age group. Osteoarthritis knee produce greater impact on physical activity and quality of life. Objective & Aim: Evaluate and Compare the effect of Dextrose prolotherapy and Platelet rich plasma therapy on Functional & Clinical outcome.
Open label comparative study was performed, were Age and sex matched, subjects with primary OA knee were enrolled in this study. Assessment & outcome of Pain and physical performance by VAS & LKI score.
A total of 72 subjects were enrolled. Mean age in Dextrose and PRP Groups were 49.94±8.28, 50.17±8.57 respectively. There was a significant improvement over time in VAS & LKI score in both groups at the end of study period.
Result of present study suggested PRP therapy is more effective in reduction in Pain & improvement in physical activity as compared to dextrose prolotharapy