Platelet Rich Plasma Therapy (PRP Therapy)

Is all Platelet Rich Plasma the same

Dr Weglein has published the first PRP textbook and lectures internationally on the topic. We have done more than 7,000 PRP treatments over the past 10 years. Dr Weglein is the only Certified PRP provider inside central Houston. We have treated patients from around the world and are proud to offer Platelet Rich Plasma therapy in Houston Texas.

What is Platelet Rich Plasma (PRP)?

PRP is the injection of the patients own platelets, in high concentration into an injured musculoskeletal area. Research has shown benefits in pain and increased functionality in many musculoskeletal disorders. Please see our published research area.

Why platelets?

When we injure ourselves, one of the first repair cells that travel to the injury are platelets. Platelets are rich in many different growth factors. These Growth factors help attract other repair cells, (neurtophils, monocytes, fibroblasts) to the damaged tissue.

Unfortunately, our tendons, ligaments and cartilage have a very poor blood supply, which leads to an incomplete or much delayed healing response. With PRP we are helping to bring these natural healing cells to an area that have been deficient.

published research has demonstrated improvements in pain and functionality.

PRP procedure

PRP is done in our office under ultrasound guidance. The procedure takes about 45 minutes in total. First a small amount of blood is taken and placed in our office centrifuge. The centrifuge separates and concentrates the platelets. Dr Weglein will then use the ultrasound to visualize the damaged tissue. The area is injected with a numbing agent, followed by the injection of PRP all done under direct MSK ultrasound guidance.

Patients should try to be off anti inflammatory medicines like ibuprofen, naprosyn, for about one week before getting PRP.

Baby Aspirin 81mg is ok to take.

Who has done this PRP

PRP has been done since 1990.

This procedure has been used by many professional teams such as:

Used in NFL, Pittsburgh Steelers, Los Angeles Dodgers, New York Mets, Houston Astros, LA clippers, Rutgers College, Mayo Clinic, Cleveland Clinic, and many more.

What area can you treat with PRP

Please see list of publications on areas prp has been studied

Post PRP MRI results

• Post PRP MRI Results

With our new Orthobiologic Clinic, we are now able to make a patient specific, unique custom prp product for each individual condition. This is the only such Orthobiologic Clinic in the Houston, allowing us to provide superior Non Surgical treatments for your musculoskeletal conditions.

• Click to watch Dr. Adam Weglein talking on PRP therapy

• Knee Pain Houston

• Chilean Miners Rescue Team Director - Patient Testimonial

• Bone on Bone Knee post Dr Weglein Unique PRP Treatments

Related Articles

• Perspectives for using platelet-rich plasma in the treatment of knee osteoarthritis: can it be improved through modifications of the protocol?
• A meta-analysis and systematic review of the clinical efficacy and safety of platelet-rich plasma combined with hyaluronic acid (PRP + HA) versus PRP monotherapy for knee osteoarthritis (KOA)
• Effect of Platelet-Rich Plasma Versus Placebo or Corticosteroid for Knee Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Controlled Trials
• Platelet Rich Plasma Effects on Knee Cartilage and Osteoarthritis Symptoms: T2, UTE-T2* and Patient Reported Outcomes Over 6-months Follow-Up
• The role of intraarticular injections of hyaluronic acid and platelet rich plasma for the treatment of articular pain in knee osteoarthritis
• Effects of platelet-rich plasma combined with exercise therapy for one year on knee osteoarthritis: retrospective cohort study
• The clinical efficacy and safety of platelet-rich plasma on frozen shoulder: a systematic review and meta-analysis of randomized controlled trials
• Ultrasound-Guided Subfascial Platelet-Rich Plasma Injections Versus Enthesis Needling for Greater Trochanteric Pain Syndrome: A Randomized Controlled Trial
• Exploring Platelet-Rich Plasma Therapy for Knee Osteoarthritis: An In-Depth Analysis
• Subacromial injection of Platelet Rich Plasma Provides Greater Improvement in Pain and Functional Outcomes Compared to Corticosteroids at 1 Year Follow- Up
• Efficacy and safety of platelet-rich plasma and hyaluronic acid combination therapy for knee osteoarthritis: a systematic review and meta-analysis
• Platelet-Poor versus Platelet-Rich Plasma for the Treatment of Muscle Injuries
• Treatment of anterior knee pain due to chondromalacia patellae with platelet-rich plasma and hyaluronic acid in young and middle-aged adults, a cohort study
• High-Platelet-Dose Platelet-Rich Plasma May Be the Nonoperative Treatment of Choice for Knee Osteoarthritis
• Utility of Platelet-Rich Plasma Therapy in the Management of Meniscus Injuries: A narrative review
• The comparison effects of intra-articular injection of Platelet Rich Plasma (PRP), Plasma Rich in Growth Factor (PRGF), Hyaluronic Acid (HA), and ozone in knee osteoarthritis; a one year randomized clinical trial
• New Infiltration Technique in the Treatment of the Plantar Fascia Syndrome Based on Platelet-Rich Plasma
• Effects of Platelet-Rich Plasma in Tear Size Reduction in Partial-Thickness Tear of the Supraspinatus Tendon Compared to Corticosteroids Injection
• Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma
• Factors affecting the features of platelet-rich plasma in patients with knee osteoarthritis
• The effect of the platelet-rich plasma and ozone therapy on tendon-to-bone healing in the rabbit rotator cuff repair model
• Efficacy of Platelet-Rich Plasma Injection on Range of Motion, Pain, and Disability in Patients with Adhesive Capsulitis: A Systematic Review and Meta-Analysis
• Evaluating the Effects of Platelet-Rich Plasma and Amniotic Viscous Fluid on Inflammatory Markers in a Human Coculture Model for Osteoarthritis
• Platelet-Rich Plasma Injections Decrease the Need for Any Surgical Procedure for Chronic Epicondylitis versus Conservative Treatment—A Comparative Study with Long-Term Follow-Up
• Effects of Intra-articular Platelet Rich Plasma on Cartilage Thickness, Clinical and Functional Outcomes in Knee Osteoarthritis
• Comparison of Clinical outcome, Cartilage turnover, and Inflammatory activity following either Intra-articular or A Combination of Intra-articular with Intra-osseous Platelet-Rich Plasma Injections in Osteoarthritis knee: A Randomized, Clinical Trial
• Platelet-Rich Plasma Injections as an Alternative to Surgery in Treating Patients With Medial Epicondylitis: A Systematic Review
• Autologous microfragmented adipose tissue and leukocyte-poor platelet-rich plasma combined with hyaluronic acid show comparable clinical outcomes for symptomatic early knee osteoarthritis over a two-year follow-up period: a prospective randomized clinical trial
• Microfragmented Adipose Tissue Versus Platelet-Rich Plasma for the Treatment of Knee Osteoarthritis: A Prospective Randomized Controlled Trial at 2-Year Follow-up
• Platelet-Rich Plasma Injection in Non-Operative Treatment of Partial-Thickness Rotator Cuff Tears: A Systematic Review and Meta-Analysis
• Platelet-rich plasma versus steroid injection in rotator cuff tendinopathies – A comparative study
• Sustained release of growth factors from photoactivated platelet rich plasma (PRP)
• Platelet-rich plasma contributes to chondroprotection by repairing mitochondrial function via AMPK/NF-κB signaling in osteoarthritic chondrocytes
• Management of Lateral Epicondylitis: A Prospective Comparative Study Comparing the Local Infiltrations of Leucocyte Enriched Platelet-Rich Plasma (L-aPRP), Glucocorticoid and Normal Saline
• Platelet-rich plasma versus hyaluronic acid in the treatment of knee osteoarthritis: a meta-analysis
• Treatment of horizontal dissection of the knee menisci with platelet-rich plasma (PRP). Literature review and analysis of own data
• Consecutive injections of leukocyte-rich platelet-rich plasma are effective in not only mild but also severe knee degeneration
• Effectiveness of ultrasound-guided platelets rich plasma injection in knee osteoarthritic cases
• Platelet-rich plasma treatment alleviates osteoarthritis-related pain, inflammation, and apoptosis by upregulating the expression levels of microRNA-375 and microRNA-337
• Multiple platelet-rich plasma injections are superior to single PRP injections or saline in osteoarthritis of the knee: the 2-year results of a randomized, double-blind, placebo-controlled clinical trial
• Platelet-rich plasma injection versus operative treatment for lateral elbow tendinosis: A systematic review and meta-analysis
• Clinical and functional outcomes following platelet rich plasma in the management of knee osteoarthritis: A case series in a tertiary care hospital
• Platelet-rich plasma versus steroids injections for greater trochanter pain syndrome: a systematic review and meta-analysis
• Platelet-rich plasma injections induce disease-modifying effects in the treatment of osteoarthritis in animal models
• The Role of Platelet-rich Plasma in Osteoarthritis of Knee-joint
• Corticosteroids or platelet-rich plasma injections for rotator cuff tendinopathy: a randomized clinical trial study
• Platelet-Rich Plasma Releasate Promotes Early Healing in Tendon After Acute Injury
• The efficacy of platelet rich plasma injections with steroid injections in treatment of lateral epicondylitis
• Effectiveness of Platelet-Rich Plasmain the Treatment of Knee Osteoarthritis
• Platelet rich plasma‐hyaluronic acid/chondrotin sulfate/carboxymethyl chitosan hydrogel for cartilage regeneration
• Platelet-rich plasma (PRP) in osteoarthritis (OA) knee: Correct dose critical for long term clinical efficacy
• Assessment of the efficacy of intra-articular platelet rich plasma treatment in an ACLT experimental model by dynamic contrast enhancement MRI of knee subchondral bone marrow and MR T2* measurement of articular cartilage
• One-year efficacy of platelet-rich plasma for moderate-to-severe carpal tunnel syndrome: A prospective, randomized, double-blind, controlled trial
• Combination of platelet-rich plasma and hyaluronic acid in the treatment of moderate and severe osteoarthritis of the knee joint
• Synergistic Effect of Nanocurcumin and Platelet Rich Plasma on Resolving Experimentally Induced Osteoarthritis in Albino Rats
• Role of intra articular injection of autologous platelet rich plasma in osteoarthrosis of the knee joint
• Platelet Rich Plasma for Treatment of Rheumatoid Arthritis: Case Series and Review of Literature
• Can the addition of ultrasound-guided genicular nerve block using 5% dextrose water augment the effect of autologous platelet rich plasma in treating elderly patients with knee osteoarthritis?
• Intradiscal Platelet-Rich Plasma Injection for Discogenic Low Back Pain and Correlation with Platelet Concentration: A Prospective Clinical Trial
• Efficacy of combined ozone and platelet-rich-plasma treatment versus platelet-rich-plasma treatment alone in early stage knee osteoarthritis
• Comparison between intra-articular infiltrations of placebo, steroids, hyaluronic and PRP for knee osteoarthritis: a Bayesian network meta-analysis
• Evaluating the efficacy of platelet rich plasma injection for the treatment of chronic plantar fasciitis
• Creating cartilage in tissue engineered chamber using Platelet rich Plasma without cell culture
• Clinical Efficacy of a Single-dose of Platelet Rich Plasma in the Management of Early Knee Osteoarthritis: A Randomized Controlled Study With Mri Assessment and Evaluation of Optimal Dose
• Comparison of the Effectiveness of Intraarticular Ozone Therapy and Platelet Rich Plasma Treatment in Patients with Knee Osteoarthritis
• Intraosseous Injections of Platelet Rich Plasma for Knee Bone Marrow Lesions Treatment: One Year Follow-Up
• High Intensity Interval Exercise Increases Platelet and Transforming Growth Factor‐ β Yield in Platelet‐Rich Plasma
• A Study on the effects of injection of platelet rich plasma (Autologous) in the management of osteoarthritis of knee joints
• Comparison of Leukocyte-Rich Platelet-Rich Plasma and Leukocyte-Poor Platelet-Rich Plasma on Achilles Tendinopathy at an Early Stage in a Rabbit Model
• Bone Marrow Aspirate ConcentrateIs Equivalent to Platelet-Rich Plasma for theTreatment of Knee Osteoarthritis at 1 Year
• Is platelet-rich plasma effective for the treatment of knee osteoarthritis? A systematic review and meta-analysis of level 1 and 2 randomized controlled trials
• Comparative Effect between Infiltration of Platelet-rich Plasma and the Use of Corticosteroids in the Treatment of Knee Osteoarthritis: A Prospective and Randomized Clinical Trial
• Comparison of two platelet rich plasma formulations with viscosupplementation in treatment of moderate grade gonarthrosis: A prospective randomized controlled study
• Treating Hand and Foot Osteoarthritis Using a Patient's Own Blood: A Systematic Review and Meta-Analysis of Platelet-Rich Plasma
• Platelet rich plasma for the treatment of coccydynia: a case report and review of Orthobiologic medicine for coccydynia
• Analysis of the clinical efficacy of platelet-rich plasma therapy in the treatment of patients with isolated facet-syndrome of the lumbar spine
• A Double-Blind, Randomized Controlled Trial Comparing Platelet-Rich Plasma versus Hyaluronic Acid for Early Osteoarthritis of the Hip Joint
• Platelet-Rich Plasma Versus Corticosteroid Injections in the Management of Elbow Epicondylitis and Plantar Fasciitis: An Updated Systematic Review and Meta-analysis
• Intra-articular platelet-rich plasma injection for knee osteoarthritis: a summary of meta-analyses
• Platelet-rich plasma combined with injectable hyaluronic acid hydrogel for porcine cartilage regeneration: a 6-month follow-up
• Treatment of degenerative meniscal tear with intrameniscal injection of platelets rich plasma
• Platelet-rich Plasma-induced Inhibition of Chondrocyte Apoptosis Directly Affects Cartilage Thickness in Osteoarthritis
• Efficiency of platelet-rich plasma therapy in knee osteoarthritis does not depend on level of cartilage damage
• Para-vertebral intramuscular platelet rich plasma vs. subcutaneous ozone injection for chronic low back pain
• Can Platelet-rich Plasma Injection Help Avoid Replacement Surgery in Osteoarthritis of the Knee?
• Investigation of Cytokine Changes in Osteoarthritic Knee Joint Tissues in Response to Hyperacute Serum Treatment
• Comparison of Platelet Rich Plasma and Prolotherapy in the Management of Osteochondral Lesions of the Talus: A Retrospective Cohort Study
• The New Treatment Approach In Knee Osteoarthritis: Efficacy Of Cellular Matrix Combination Of Platelet Rich Plasma With Hyaluronic Acid Versus Two Different Types Of Hyaluronic Acid (Ha) (Prospective, Randomized, Double Blind Control Study)
• Comparative Analysis Of The Effectiveness And Tolerance Of Intra-articular Injection Of Platelet Rich Plasma Vs Hyaluronic Acid And Non-arthroscopic Joint Lavage In Patientswith Knee Osteoarthritis
• The Concentration of Plasma Provides Additional Bioactive Proteins in Platelet and Autologous Protein Solutions
• Percutaneous injections of Platelet rich plasma for treatment of intrasubstance meniscal lesions
• Single intra-articular platelet-rich plasma versus corticosteroid injections in the treatment of adhesive capsulitis of the shoulder: a cohort study.
• Injecting autologous platelet rich plasma solely into the knee joint is not adequate in treating geriatric patients with moderate to severe knee osteoarthritis.
• Mechanistic insight into hyaluronic acid and platelet-rich plasma-mediated anti-inflammatory and anti-apoptotic activities in osteoarthritic mice.

• Evaluating the Effectiveness of Platelet-Rich Plasma for Treating Lateral Epicondylitis
• Intra-articular Platelet Rich Plasma versus Corticosteroid in Treatment of Knee Osteoarthritis Patients
• Efficacy of Platelet-Rich Plasma Injection in the Management of Lateral Epicondylitis: A Retrospective Assessment
• Platelet Rich Plasma Versus Corticosteroid Injections in Treatment of Knee Osteoarthritis
• Intrarticular Autologous Platelet-Rich Plasma Versus Methyl Prednisolone Acetate In Adhesive Capsulitis Of Shoulder: A Comparative Study
• A Comparison of the Results of Platelet-Rich Plasma Injection Versus the Results of Corticosteroid Injections in De-Quervain Tenosynovitis
• Revolutionizing Back Pain Management: Is Epidural Platelet-Rich Plasma the Superior Choice Over Steroids?
• The efficacy and functional outcome of intra-articular infiltration of autologous platelet rich plasma in early osteoarthritis knee
• Analysis of IL-6 marker in synovial fluid of the knee joint in patients with osteoarthritis and rheumatoid arthritis before and after platelet-rich plasma administration
• Platelet-Rich Plasma Therapy: An Effective Approach for Managing Knee Osteoarthritis
• Effectiveness and safety of an ultrasound-guided injection of platelet-rich plasma versus sodium hyaluronate in patients with knee osteoarthritis
• Platelet-Rich Plasma Injections for Frozen Shoulder: Efficacy in Pain Reduction and Shoulder Function Improvement
• Platelet-rich plasma preserves cartilage thickness and delays total knee arthroplasty in osteoarthritis with an inflammatory phenotype: a 5-year follow-up retrospective study
• A comparative study to assess the clinical outcomes in osteoarthritis of the knee between intra-articular platelet rich plasma (PRP) injections vs intra-articular corticosteroid injections
• Using Platelet-Rich Plasma to Treat DeQuervain's Tenosynovitis and Cortisone-Induced Skin Discoloration and Atrophy: A Case Study
• Platelet-rich plasma in the management of trigger finger: A case report
• A comparative prospective study of platelet rich plasma vs corticosteroid injection in lateral epicondylitis
• The mechanism of action of platelet-rich plasma for knee osteoarthritis: a systematic review
• Clinical and Functional Outcome of Meniscal Injuries Treated with Platelet-Rich Plasma: A Single-Center Case Series
• Comparison of Local Corticosteroids versus Plasma Rich Protein for Management of Rotator Cuff Tendinopathy
• Role of Platelets in Osteoarthritis—Updated Systematic Review and Meta-Analysis on the Role of Platelet-Rich Plasma in Osteoarthritis
• Cell Multiplication in Platelet Rich Fibrin (PRF) and Platelet Rich Plasma (PRP) as Biofuels for Cartilage Tissue Engineering
• Comparison of platelet-rich plasma and extracorporeal shock wave therapy in patients with chronic lateral epicondylitis: A prospective, randomized-controlled study
• Successful Treatment of Anterolateral Ligament Tear of the Knee with Ultrasound-guided Platelet-Rich Plasma Injection
• The Effects Of Injecting Intra Articular Platelet-rich Plasma On Pain Scores In Knee Joint Osteoarthritis
• A better functional outcome with platelet rich plasma compared with local steroid injection in tennis elbow
• Platelet-Rich Plasma versus Corticosteroid Injection for the Treatment of Lateral Epicondylitis: A Systematic Review of Systematic Reviews
• The Efficacy of Injections for Partial Rotator Cuff Tears: A Systematic Review
• Intra-articular Platelet-Rich Plasma Injections for Treating Knee Pain Associated with Articular Cartilage and Degenerative Meniscal Lesions
• Comparison of steroid injection and platelet-rich plasma injection in the treatment of chronic lateral Epicondylitis
• Treatment of unresolved lower back pain with platelet-rich plasma injections
• Chondrogenic Effect of Intra-articular Hypertonic-Dextrose (Prolotherapy) in Severe Knee Osteoarthritis
• Comparative Study of Local Injection of Platelet Rich Plasma versus Corticosteroids in the Treatment of Lateral Epicondylitis
• High-field MRI exploration of the structural effects of cellular matrix^™ on articular cartilage in knee osteoarthritis
• Assessment of the role of platelet rich plasma (PRP) in mild to moderate osteoarthritis knee joint using VAS and WOMAC score
• Comparative evaluation of leukocyte- and platelet-rich plasma and pure platelet-rich plasma for cartilage regeneration in a cartilage defects model in rabbits
• A novel treatment of knee degenerative disorders all-in-one intra-articular injection of platelet-rich plasma combined with hyaluronic acid
• Knee OA management: A cost-effectiveness analysis of platelet-rich-plasma versus hyaluronic acid for the intra-articular treatment of knee OA in France.
• Efficacy of platelet-rich plasma administration in patients with severe knee osteoarthritis
• A comparison of the use of PRP Versus Hypertonic glucose in the treatment of physiotherapy resistant sacroiliac joint Incompetence
• Treatment of lateral epicondylitis with autologous platelet rich plasma injection
• The use of Platelet Rich Plasma in the Management of Plantar Fasciitis: A Systematic Review
• Comparative Effect Of Dextrose Prolotherapy And Platelet Rich Plasma Therapy In Primary Osteoarthritis Knee
• Volumetric findings of MRI after platelet rich plasma injection in knee osteoarthritis (A randomized clinical trial)
• Platelet-rich plasma and corticosteroid injection in lateral epicondylitis: Who is great
• Platelet-Rich Plasma, Hydroxyapatite and Chitosan in the Bone and Cartilaginous Regeneration of Femoral Trochlea in Rabbits: Clinical, Radiographic and Histomorphometric Evaluations
• AB0975 Does platelet rich plasma change the volumetric findings of mri imaging? (A Randomised Clinical Trial).
• Platelet Rich Plasma Practical Use in Non-Surgical Musculoskeletal Pathology.
• Platelet-rich plasma therapy in refractory knee osteoarthritis combined with infection
• Cell therapy for the Treatment of Knee Osteoarthritis: A Comprehensive Review
• The Clinical Outcomes are Associated with Changes in the Ultrasonography Structural Appearance After Platelet-Rich Plasma Treatment for Knee Osteoarthritis
• To evaluate the effect of combining photo-activation therapy with platelet-rich plasma injections for the novel treatment of osteoarthritis
• Photoactivated platelet-rich plasma therapy for a traumatic knee chondral lesion.

• Platelet Rich Plasma Research Publications

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