Monthly Archives: September 2014

Pain in Osteoarthritis: Can Prolotherapy Help?

Osteoarthritis (OA) remains the most common joint disease in the world, and to date, has no cure. Approximately 27 million people in the United States (1) suffer from OA, which is characterized by chronic pain, joint stiffness, structural damage, and … Continue reading

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Does intra articular platelet rich plasma injection improve function, pain and quality of life in patients with osteoarthritis of the knee? A randomized clinical trial

Abstract We designed a randomized clinical trial with control group, to investigate the effects of platelet rich plasma (PRP) on pain, stiffness, function and quality of life in patients with knee osteoarthritis. Patients were randomly divided in two groups. For … Continue reading

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Corticosteroid versus platelet-rich plasma injection in epicondylitis

Abstract Lateral epicondylitis (LE) is often considered an inflammatory disease characterized by tendon microtears that are followed by an incomplete reparative response that leads to chronic pain and decreased function on the upper extremity. A modality that is commonly used … Continue reading

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Comparison of the therapeutic effects of ultrasound-guided platelet-rich plasma injection and dry needling in rotator cuff disease: a randomized controlled trial

Abstract OBJECTIVE: To compare the effects of platelet-rich plasma injection with those of dry needling on shoulder pain and function in patients with rotator cuff disease. DESIGN: A single-centre, prospective, randomized, double-blinded, controlled study. SETTING: University rehabilitation hospital. Read more

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Platelet-Rich Plasma: A Promising Therapy for Recalcitrant Venous Leg Ulcer: A Case Report

Abstract Venous disease is the most common cause of leg ulcers with considerable morbidity and a dramatic negative impact on patient’s quality of life. Platelet-rich plasma (PRP) is an autologous preparation of platelets in concentrated plasma and contains various growth … Continue reading

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Dextrose prolotherapy for knee osteoarthritis: a randomized controlled trial

Abstract PURPOSE: Knee osteoarthritis is a common, debilitating chronic disease. Prolotherapy is an injection therapy for chronic musculoskeletal pain. We conducted a 3-arm, blinded (injector, assessor, injection group participants), randomized controlled trial to assess the efficacy of prolotherapy for knee … Continue reading

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Efficacy of Autologous Bone Marrow Concentrate for Knee Osteoarthritis with and without Adipose Graft

Introduction Knee osteoarthritis (OA) is a significant health problem with increasing impact on public health [1]. In 2009 there were approximately 600,000 total knee arthroplasties (TKAs) performed for knee OA, more than double the number performed 10 years earlier [2]. … Continue reading

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Hyperuricemic PRP in Tendon Cells

Introduction The use of platelet-rich plasma (PRP) to treat tendon pathology has widely expanded in the last five years [1]. PRP is injected within tendons aiming at healing, reducing pain, and improving tendon function [2]. A recent meta-analysis has shown … Continue reading

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Microperforation prolotherapy: a novel method for successful nonsurgical treatment of atraumatic spontaneous anterior sternoclavicular subluxation, with an illustrative case

Abstract BACKGROUND: Surgical repair of an atraumatic spontaneous anterior subluxation of the sternoclavicular joint (herein referred to as the “SCJ”) is often associated with poor outcome expectations. With traditional treatment, successful conservative therapy usually incorporates major lifestyle alterations. This manuscript … Continue reading

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Clinical Applications of Platelet-Rich Plasma in Patellar Tendinopathy

Abstract Platelet-rich plasma (PRP), a blood derivative with high concentrations of platelets, has been found to have high levels of autologous growth factors (GFs), such as transforming growth factor-β (TGF-β), platelet-derived growth factor (PDGF), fibroblastic growth factor (FGF), vascular endothelial … Continue reading

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