Role of Platelet Rich Plasma Gel in Bone Healing of Black Bengal Goats

Role of Platelet Rich Plasma Gel in Bone Healing of Black Bengal Goats

Abstract

The study was conducted to evaluate homogenous platelets rich plasma (PRP) gel in the bone healing process. There are limited researches on the use of biomaterials to assist healing process in Bangladesh done earier. Therefore, this experiment was carried out to exploit the therapeutic effects of PRP gel on healing process. For bone healing study, total 6 oblique tibial fracture cases in goats were created. Goats were divided into three groups with two animals in each group bearing weight 15-20 kg and age 1-3 years. Among these two groups were treated with homogenous PRP gel and one group was untreated served as control and fracture cases were corrected with open reduction and internal fixation using bone plate with screw and surgical stainless steel wire (18 Gauze) suture. Goats showed a satisfactory result on bone healing after using PRP gel. Post operative radiography confirmed that bone fragments were well maintained until healing occurred and radiograph showed negligible callus at 30 days, complete healing occur. On the other hands, it takes 60 days for immobilization in untreated group. In treatment groups there was no periosteal reaction at the fracture site. No postoperative complication was observed at surgical site. This study could help veterinarians to consider natural biomaterial product specially homogenous PRP gel for a good healing of bone with minimum complications. Further studies are necessary for the molecular investigation of healing process and proper establishment of commercially available of PRP gel in our country and easyiest way of application.

Abstract

The study was conducted to evaluate homogenous platelets rich plasma (PRP) gel in the bone healing process. There are limited researches on the use of biomaterials to assist healing process in Bangladesh done earier. Therefore, this experiment was carried out to exploit the therapeutic effects of PRP gel on healing process. For bone healing study, total 6 oblique tibial fracture cases in goats were created. Goats were divided into three groups with two animals in each group bearing weight 15-20 kg and age 1-3 years. Among these two groups were treated with homogenous PRP gel and one group was untreated served as control and fracture cases were corrected with open reduction and internal fixation using bone plate with screw and surgical stainless steel wire (18 Gauze) suture. Goats showed a satisfactory result on bone healing after using PRP gel. Post operative radiography confirmed that bone fragments were well maintained until healing occurred and radiograph showed negligible callus at 30 days, complete healing occur. On the other hands, it takes 60 days for immobilization in untreated group. In treatment groups there was no periosteal reaction at the fracture site. No postoperative complication was observed at surgical site. This study could help veterinarians to consider natural biomaterial product specially homogenous PRP gel for a good healing of bone with minimum complications. Further studies are necessary for the molecular investigation of healing process and proper establishment of commercially available of PRP gel in our country and easyiest way of application.

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