Tag Archives: platelet rich plasma

The effects of injecting intra-articular platelet-rich plasma or prolotherapy on pain score and function in knee osteoarthritis

Abstract Introduction: Osteoarthritis (OA) is a chronic joint disease that usually occurs in older people and leads to pain and disabilities. OA treatment ranges from drug therapy to surgery. Drug and rehabilitation therapy are preferred over surgery, and, especially, there … Continue reading

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Concentrations of Blood Components in Commercial Platelet-Rich Plasma Separation Systems: A Review of the Literature

Abstract Background: Platelet-rich plasma (PRP) has proven to be a very safe therapeutic option in the treatment of tendon, muscle, bone, and cartilage injuries. Currently, several commercial separation systems are available for the preparation of PRP. The concentrations of blood … Continue reading

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Platelet-rich plasma inhibits Wnt/β-catenin signaling in rabbit cartilage cells activated by IL-1β

Abstract Objective: Platelet-rich plasma (PRP) has been reported to alleviate degenerative pathological damage to joint cartilage. This study aimed to investigate the effect of PRP on Wnt/β-catenin signaling in rabbit chondrocytes. Methods: Using 3-month-old New Zealand white rabbits, PRP was … Continue reading

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Freeze-Dried Chitosan-PRP Injectable Surgical Implants for Meniscus Repair: Pilot Feasibility Studies in Ovine Models

Abstract Clinical management of meniscus tears often involves partial meniscectomy, which can lead to Osteoarthritis (OA). Meniscus repair augmentation strategies are being developed to compensate for the tissue’s limited healing response. The purpose of the study was to assess the … Continue reading

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Injectable-platelet rich fibrin using the low speed centrifugation concept improves cartilage regeneration when compared to platelet-rich plasma

Abstract The aim of the present study was to evaluate the effect of injectable platelet-rich fibrin (i-PRF) on cultivated chondrocytes and osteochondral regeneration in critical-sized osteochondral defect of the rabbit’s knee in comparison to autologous platelet-rich plasma (PRP). Chondrocytes were … Continue reading

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Men and Women Differ in the Biochemical Composition of Platelet-Rich Plasma

Abstract Background: Autologous platelet-rich plasma (PRP) is widely used for a variety of clinical applications. However, clinical outcome studies have not consistently shown positive effects. The composition of PRP differs based on many factors. An improved understanding of factors influencing … Continue reading

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Platelet Rich Plasma Supports Proliferation and Re-differentiation of Chondrocytes during In Vitro Expansion

Abstract Articular cartilage regeneration is insufficient to restore sports injuries or defects that can occur from trauma. Treatment options for cartilage repair include autologous chondrocyte implantation (ACI) by isolation, expansion, and reimplantation of healthy donor chondrocytes. Chondrocyte expansion onto 2D … Continue reading

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Platelet-rich plasma: combinational treatment modalities for musculoskeletal conditions

Abstract Current research on common musculoskeletal problems, including osteoarticular conditions, tendinopathies, and muscle injuries, focuses on regenerative translational medicine. Platelet-rich plasma therapies have emerged as a potential approach to enhance tissue repair and regeneration. Platelet-rich plasma application aims to provide … Continue reading

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Role of platelet rich plasma in patients of osteoarthritis knee-a prospective study

Abstract Introduction: In the present study, we evaluated the effects of 2 courses of PRP injections with 3 weeks interval, on patient’s quality of life and functional ability. Materials and Method: It was a prospective study carried out on 55 … Continue reading

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Clinical and economic effectiveness of the use of platelet-rich plasma in the treatment of chronic wounds

Abstract: The paper presents the results of the clinical use of platelet-rich plasma in the treatment of long-term non-healing wounds of various etiologies in patients on inpatient treatment and outpatient monitoring in the department of surgical infections of the State-financed … Continue reading

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