Monthly Archives: January 2017

Technical Innovation Case Report: Ultrasound-Guided Prolotherapy Injection for Insertional Achilles Calcific Tendinosis

Abstract: We describe the use of ultrasound guidance for hyperosmolar dextrose (prolotherapy) injection of the distal calcaneal tendon specifically just anterior to identified enthesophytes in patients with insertional Achilles calcific tendinosis refractory to conservative treatment. This specific technique has not … Continue reading

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Effect of ozone and methylprednisolone treatment following crush type sciatic nerve injury.

Abstract: Purpose: To assess and compare the histopathological effects of ozone therapy and/or methylprednisolone (MPS) treatment on regeneration after crush type sciatic nerve injury. Methods: Forty Sprague-Dawley male rats were randomly allocated into four groups. Four groups received the following … Continue reading

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The temporal effect of platelet-rich plasma on pain and physical function in the treatment of knee osteoarthritis: systematic review and meta-analysis of randomized controlled trials

Abstract: Background: Quite a few randomized controlled trials (RCTs) investigating the efficacy of platelet-rich plasma (PRP) for treatment of knee osteoarthritis (OA) have been recently published. Therefore, an updated systematic review was performed to evaluate the temporal effect of PRP … Continue reading

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Protective Nature of Platelet-Rich Plasma Against Chondrocyte Death When Combined With Corticosteroids or Local Anesthetics

Abstract: Background: The use of corticosteroids and local anesthetics to treat osteoarthritis has established benefits, including relief of pain and increased range of motion, but may also have the potential to lead to tissue atrophy or degeneration, specifically on chondrocytes. … Continue reading

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Generation of stem cell-based bioartificial anterior cruciate ligament (ACL) grafts for effective ACL rupture repair

Abstract: Introduction: Regenerative medicine (RM) is an interdisciplinary field of research and clinical applications focus on the repair, replacement, or regeneration of cells, tissues and organs to restore impaired function. RM employs technological breakthroughs such as those used in tissue … Continue reading

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A Randomized Controlled Study to Evaluate the Effectiveness of Local Platelet Rich Plasma (PRP) Injection for the Management of the Cases of Planter Fasciitis – Final Outcome of 179 Cases at 12 Months

Abstract: Introduction: Plantar fasciitis is an inflammation of the plantar fascia at the bottom of the foot. Though pathology of plantar fasciitis remains ill understood, there is evidence to suggest that it is probably initiated by repeated micro trauma. Numerous … Continue reading

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Comparison of different methods of centrifugation for preparation of platelet – rich plasma (PRP)

Abstract: Introduction: Platelet-rich plasma(PRP) has wide clinical applications which have been proved by various studies. There are various methods available now a days to prepare PRP but no standard protocol determining the time and centrifugation speed is available. This variation … Continue reading

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Clinical effectiveness in severe knee osteoarthritis after intra-articular platelet-rich plasma therapy in association with hyaluronic acid injection: three case reports

Abstract: Osteoarthritis (OA) is a degenerative disorder resulting from loss of joint cartilage and underlying bone and causes pain and loss of function. The treatment ofk:nee OA is still a challenge because of the poor self-regeneration capacity of artilage. The … Continue reading

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Efficacy of platelet-rich plasma for clinical outcomes after total knee arthroplasty: a systematic review and meta-analysis

Abstract: Objective: The purpose of this systematic review and meta-analysis of randomized controlled trials (RCTs) and non-RCTs were to evaluate the effect of platelet-rich plasma (PRP) versus placebo on the patients receiving total knee arthroplasty (TKA). Methods: In April 2016, … Continue reading

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