Monthly Archives: November 2016

Platelt-Rich Plasma Enhances Cartilage Integration: A BioEngineered In Vitro Model

Abstract: Osteoarthritis (OA) is a debilitating disease characterised by degradation of articular cartilage and subchondral bone remodeling. Current therapies for early or midstage disease do not regenerate articular cartilage, or fail to integrate the repair tissue with host tissue, and … Continue reading

Posted in General | Leave a comment

Prolotherapy for Lumbar Segmental Instability Associated with Degenerative Disc Disease

Abstract: Prolotherapy is an injection-based therapy that may be used in the management of chronic low back pain. In principle, injection solutions are formulated to produce an inflammatory response, which in turn promotes ligamentous and tendinous regeneration. This case study … Continue reading

Posted in General | Leave a comment

Injection Therapy: Intra-articular Platelet-Rich Plasma and Stem Cell Therapy

Abstract: Platelet-rich plasma (PRP) has been touted in the sports medicine and orthopaedic surgery communities as a remedy with the ability to bridge the gap between conservative, pain relieving therapies and surgical interventions. Its theoretical advantages include its ability to … Continue reading

Posted in General | Tagged , , , , | Leave a comment

Comparative effectiveness of dextrose prolotherapy versus control injections and exercise in the management of osteoarthritis pain: a systematic review and meta-analysis

Abstract: Background: Increasing evidence has supported the use of dextrose prolotherapy for patients with osteoarthritis. However, the real benefits may be affected by differences in injection protocols, comparative regimens, and evaluation scales. Methods: PubMed and Scopus were searched from the … Continue reading

Posted in General | Leave a comment

Valutazione economica sull’utilizzo de; plasma arricchito di piastrine vs acide ialuronico per iltrattamento dell’osteoartrosi al ginocchio.

Abstract: Porpose: The incresing the incidence of total joint arthroplasty reflects the rises of osteoarthritis (OA) prevalence. OA is a degenerative pathalogy affecting joints with a significant impact on quality of life causing pain, leading to social lfe limitations and … Continue reading

Posted in General | Tagged , , , , , | Leave a comment

Use of Platelet-rich Plasma in an Experimental Rheumatoid Arthritis Model

Abstract: Rheumatoid arthritis (RA) is characterized by an autoimmune activity against the synovial membrane, leading to a clinical picture of synovitis. Platelet-rich plasma (PRP) can be an alternative treatment for RA. This study evaluated PRP as a treatment for RA … Continue reading

Posted in General | Tagged , , , | Leave a comment

Synergistic anabolic actions of hyaluronic acid and platelet-rich plasma on cartilage regeneration in osteoarthritis therapy.

Abstract: Osteoarthritis (OA) is a common disease associated with tissue inflammation, physical disability and imbalanced homeostasis in cartilage. For advanced treatments, biological approaches are currently focused on tissue regeneration and anti-inflammation. This study was undertaken to evaluate the therapeutic efficacies … Continue reading

Posted in General | Leave a comment

Intradiscal and intra articular facet infiltrations with plasma rich in growth factors reduce pain in patients with chronic low back pain

Abstract: Context: Low back pain (LBP) is a complex and disabling condition, and its treatment becomes a challenge. Aims: The aim of our study was to assess the clinical outcome of plasma rich in growth factors (PRGF Endoret) infiltrations (one … Continue reading

Posted in General | Tagged , , , , | Leave a comment

Prospective randomized clinical study for the treatment of laterat epicondylitis: Comparison among PRP (Platelet-Rich-Plasma), Prolotherapy Physiotherapy and ESWT

Abstract: As recent knowledge proved that pathology of lateral epicondylitis is no more an inflammatory condition, but angiofibroblastic degeneration, steroid injection is no more recommended for lateral epicondylitis. It seems to be inappropriate that most of the comparative study used … Continue reading

Posted in General | Leave a comment

Dextrose Prolotherapy: A Narrative Review of Basic Science, Clinical Research, and Best Treatment Recommendations

Abstract: Background:Prolotherapy is an injection-based treatment of chronic musculoskeletal pain. A general surgeon in the United States, George Hackett, formalized injection protocols in the 1950s, based on 30 years of clinical experience.1 Prolotherapy has been identified as a regenerative injection … Continue reading

Posted in General | Leave a comment