Monthly Archives: October 2014

Onlay Bone Graft Maintenance Using Guided Bone Regeneration, Platelet Rich Plasma, and Their Combination

Abstract Onlay bone grafts have a bad reputation of resorption with loss of contour and volume. Rigid fixation reduces the incidence of resorption but does not prevent it. Literature shows reduction of resorption by applying guided bone regeneration (GBR) barriers … Continue reading

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Gelatin hydrogel impregnated with platelet-rich plasma releasate promotes angiogenesis and wound healing in murine model

Abstract Platelet-rich plasma (PRP) contains numerous growth factors to promote wound healing and angiogenesis. The objective of this study was to explore the efficacy of biodegradable gelatin hydrogel impregnated with PRP releasate (PRPr) in the wound healing process compared with … Continue reading

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Platelet-rich plasma: evidence for the treatment of patellar and Achilles tendinopathy-a systematic review

Abstract Platelet-rich plasma (PRP) has been introduced in the clinical practice to treat a growing number of different musculoskeletal pathologies. It is currently applied in the treatment of Achilles and patellar tendinopathies, which are common sport-related injuries very challenging to … Continue reading

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Chronic neck pain: making the connection between capsular ligament laxity and cervical instability

Abstract The use of conventional modalities for chronic neck pain remains debatable, primarily because most treatments have had limited success. We conducted a review of the literature published up to December 2013 on the diagnostic and treatment modalities of disorders … Continue reading

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Intra-articular injection of mesenchymal stem cells leads to reduced inflammation and cartilage damage in murine antigen-induced arthritis

Abstract BACKGROUND: Rheumatoid arthritis (RA) is a debilitating and painful disease leading to increased morbidity and mortality and novel therapeutic approaches are needed. The purpose of this study was to elucidate if mesenchymal stem cells (MSCs) injected in the joints … Continue reading

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Cartilage regeneration by chondrogenic induced adult stem cells in osteoarthritic sheep model

Abstract OBJECTIVES: In this study, Adipose stem cells (ADSC) and bone marrow stem cells (BMSC), multipotent adult cells with the potentials for cartilage regenerations were induced to chondrogenic lineage and used for cartilage regenerations in surgically induced osteoarthritis in sheep … Continue reading

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One-Step Cartilage Repair with Bone Marrow Aspirate Concentrated Cells and Collagen Matrix in Full-Thickness Knee Cartilage Lesions Results at 2-Year Follow-up

Abstract Objective: The purpose of our study was to determine the effectiveness of cartilage repair utilizing 1-step surgery with bone marrow aspirate concentrate (BMAC) and a collagen I/III matrix (Chondro-Gide, Geistlich, Wolhusen, Switzerland). Materials and Methods: We prospectively followed up … Continue reading

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Orthobiologics: Is it a game changer in Regenerative Orthopaedics?

In the past 20 years, the field of medicine has witnessed an unprecedented rate of scientific discovery and experiments for newer materials to promote healing and the regenerative capacity of the human tissues and the use of biologic tissues for … Continue reading

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The use of platelet-rich plasma for the treatment of osteoarthritis

Abstract Osteoarthritis (OA) is the most common cause of disability in the United States. With an aging population, its incidence is only likely to rise. Articular cartilage has a poor capacity to heal. The advent of regenerative medicine has heralded … Continue reading

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Platelet-Rich Plasma Injections for the Treatment of Hamstring Injuries

Abstract Background: A hamstring injury is one of the most common types of injury affecting athletes. Despite this, the optimal management of hamstring muscle injuries is not yet defined. The effect of autologous platelet-rich plasma (PRP) therapy on the recovery … Continue reading

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