Monthly Archives: October 2013

A novel hypothesis: the application of platelet-rich plasma can promote the clinical healing of white-white meniscal tears

Abstract The white-white tears (meniscus lesion completely in the avascular zone) are without blood supply and theoretically cannot heal. Basal research has demonstrated that menisci are unquestionably important in load bearing, load redistribution, shock absorption, joint lubrication and the stabilization … Continue reading

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A metaanalysis of the effectiveness and safety of ozone treatments for herniated lumbar discs

Abstract PURPOSE: To determine statistically significant effects of oxygen/ozone treatment of herniated discs with respect to pain, function, and complication rate. MATERIALS AND METHODS: Random-effects metaanalyses were used to estimate outcomes for oxygen/ozone treatment of herniated discs. A literature search … Continue reading

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Prolotherapy case

Regenerative injection therapy with whole bone marrow aspirate for degenerative joint disease: a case series. Hauser RA, et al. Clin Med Insights Arthritis Musculoskelet Disord. 2013 Read more

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Autologous bone marrow concentrate: review and application of a novel intra-articular orthobiologic for cartilage disease

Abstract Younger adults, aged < 65 years, increasingly present to their physicians with advanced cartilage disease or post-traumatic osteoarthritis. A number of treatments exist for lessening patient pain and improving patient function. However, many patients are becoming aware of the … Continue reading

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Platelet-rich plasma for managing pain and inflammation in osteoarthritis

Abstract Osteoarthritis (OA) is a common disease involving joint damage, an inadequate healing response and progressive deterioration of the joint architecture. Autologous blood-derived products such as plateletrich plasma (PRP) are key sources of molecules involved in tissue repair and regeneration. … Continue reading

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Platelet-rich plasma for managing pain and inflammation in osteoarthritis

Abstract Osteoarthritis (OA) is a common disease involving joint damage, an inadequate healing response and progressive deterioration of the joint architecture. Autologous blood-derived products, such as platelet-rich plasma (PRP), are key sources of molecules involved in tissue repair and regeneration. … Continue reading

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Autologous Platelet-Rich Plasma Versus Dextrose Prolotherapy for the Treatment of Chronic Recalcitrant Plantar Fasciitis

Abstract OBJECTIVE: To determine the efficacy of autologous platelet-rich plasma (PRP) compared with dextrose prolotherapy (DP) in patients with chronic recalcitrant plantar fasciitis (PF) DESIGN: A single-blinded, randomized, controlled study. SETTING: Department of Physical Medicine and Rehabilitation of a university … Continue reading

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Oxygen/ozone as a medical gas mixture. A critical evaluation of the various methods clarifies positive and negative aspects

Abstract Besides oxygen, several other gases such as NO, CO, H2, H2S, Xe and O3 have come to age over the past few years. With regards to O3, its mechanisms of action in medicine have been clarified during the last … Continue reading

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Supplementation With Platelet-Rich Plasma Improves the In Vitro Formation of Tissue-Engineered Cartilage With Enhanced Mechanical Properties

Purpose This study aimed to determine the effects of platelet-rich plasma (PRP) on the histologic, biochemical, and biomechanical properties of tissue-engineered cartilage. Methods Chondrocytes isolated from bovine metacarpal-phalangeal articular cartilage were seeded on top of a porous ceramic substrate (calcium … Continue reading

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Prolotherapy: a clinical review of its role in treating chronic musculoskeletal pain

Abstract Prolotherapy is a technique that involves the injection of an irritant, usually a hyperosmolar dextrose solution, typically in the treatment of chronic painful musculoskeletal conditions. Despite its long history and widespread use as a form of complementary therapy, there … Continue reading

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